Фотодинамическая терапия цервикальной интраэпителиальной неоплазии Т. П. Лапцевич, Ю. П. Истомин und

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Преобладающий возраст 50 60 лет. Рак болезнь — Сюда установлено перенаправление со страницы Рак заболевание. Согласно общепринятой в русском языке медицинской терминологии, под раком подразумевают только злокачественные новообразования из эпителиальной ткани.

Мы используем куки для наилучшего представления нашего сайта. Продолжая использовать данный сайт, вы соглашаетесь с этим. Рак шейки матки — инвазивный процесс, начинающийся обычно в месте перехода многослойного плоского эпителия в однослойный цилиндрический и представленный либо многослойным плоским, либо железистым эпителием.

Частота рака шейки матки — 15,1 на Её используют в сочетании с хирургическим лечением при больших 4 см и более опухолях на стадиях IБ и IIА и химиотерапией гидроксимочевина, цисплатин и фторурацил при развитых локализованных опухолях на стадиях IIБ-IVA.

В настоящее время она применяется для лечения онкологических, глазных и кожных заболеваний. В качестве фотосенсибилизаторов используют соединения на основе протопорфирина IX, фталоцианинов или их предшественников, которые вводят внутривенно или наносят локально на кожу или слизистые оболочки.

Разрабатываются подходы к созданию методов и процедур ФДТ с помощью кремниевых наночастиц, покрытых нанопленкой из атомов золота нанораковины, nanoshells. Фотосенсибилизаторы накапливаются в зоне опухоли по причине большей проницаемости опухолевых сосудов и более высокой метаболической активности опухолевых клеток. Методы адресной доставки химических фотосенсибилизаторов, основанные на их специфическом взаимодействии с опухолевыми и другими клетками, пока недостаточно разработаны.

В качестве источника света в настоящее время используется излучение лазера в красной области видимого спектра, которое направляется врачом на пораженный участок с помощью световода. В результате такого воздействия клетки, включившие фотосенсибилизатор, погибают вследствие избыточного накопления в них активных форм кислорода, нарушающих большинство клеточных функций. В случае золотых наночастиц происходит сильный разогрев клеток и их гибель.

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